diff --git a/websocket-sharp/Net/HttpListenerResponse.cs b/websocket-sharp/Net/HttpListenerResponse.cs
index ab40ad6d..062c1ce4 100644
--- a/websocket-sharp/Net/HttpListenerResponse.cs
+++ b/websocket-sharp/Net/HttpListenerResponse.cs
@@ -342,6 +342,11 @@ namespace WebSocketSharp.Net
         if (_disposed)
           throw new ObjectDisposedException (GetType ().ToString ());
 
+        if (_headersSent) {
+          var msg = "The response is already being sent.";
+          throw new InvalidOperationException (msg);
+        }
+
         if (value == null) {
           _contentType = null;
           return;